" - 10 Second Closure - Closing the Gap in Tissue Repair"

Aponos Medical Corp has a breakthrough surgical tissue management technology to simplify complex surgical procedures using minimally invasive approaches. This product technology with reimbursement ready, turnkey revenue opportunities, such as Endoscopic Submucosal Dissection (ESD) and Endoscopic Mucosal Resection (EMR) has an estimated $600M - $1B in global growth potential in the rapidly evolving MIS (minimally invasive surgery) arena.
[CLICK] The Slide Show to see the Aponos Padlock Clip and Lock-It Delivery System Demo

Aponos products are simple to operate single patient use devices that provide the surgeon/endoscopist with extremely powerful treatment options for their patients. These products combine a low profile tissue management and closure device, [Padlock-Clip], with a precise positioning/delivery system, [Lock-It Delivery System] to deliver a time saving “point and shoot” product for endoscopically controlling tissue which will safely, quickly and effectively manage tissue during surgery including:

• Provide a means to close tissue defects, natural or man made, such as holes, fistulas, or incisions.
• Provide a means of localizing, collecting and isolating a large volume of tissue required
  for effective Endoscopic Submucosal Dissection (ESD).
• Providing a means of raising targeted tissue up from the local surface, and locking it,
  ensuring a clear field of view and stability for Endoscopic Mucosal Resection (EMR).
• Provide a means to attach and/or anchor other theraputic devices to tissue surfaces.

Procedures are accomplished remotely using state of the art minimally invasive surgical (“MIS”) techniques in practice today, complimented by the unique adaptability of the Aponos Lock-It Delivery System to easily mount and fit on the wide range and styles of existing off the shelf endoscopic devices.

Padlock-G® Clinical Demonstrations and Performance Studies

• Padlock-G® Esophageal Closure Sequence
• Padlock-G® Colon Closure Sequence
  
• Carlos Guarner-Argente, Henry Córdova, Graciela Martínez-Pallí, Ricard Navarro, Miriam Cuatrecasas, Cristina Rodríguez de Miguel, Mireia Beltrán, Antonio M. Lacy, Angels Ginès, Maria Pellisé, Josep Llach, Glòria Fernández-Esparrach et al.
  "Yes, we can: reliable colonic closure with the Padlock-G clip in a survival porcine study (with video)" Gastrointestinal Endoscopy Vol. 72, Issue 4, Pages 841-844
• David J. Desilets, John R. Romanelli, David B. Earle, Christopher N. Chapman.
  "Gastrotomy Closure with the Lock-It System and the Padlock-G clip: A Survival Study in a Porcine Model" Journal of Laparoendoscopic & Advanced Surgical Techniques doi:10.1089/lap.2010.0076.
• J. R. Romanelli, D. J. Desilets, D. B. Earle
  "Natural orifice transluminal endoscopic surgery gastrotomy closure in porcine explants with the Padlock-G clip using the Lock-It system" Endoscopy 2010; 42(4): 306-310 DOI: 10.1055/s-0029-1243950